Current Challenges and Future Directions in Peptidomics

Michael Schrader, Lloyd D. Fricker

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The field of peptidomics has been under development since its start more than 20 years ago. In this chapter we provide a personal outlook for future directions in this field. The applications of peptidomics technologies are spreading more and more from classical research of peptide hormones and neuropeptides towards commercial applications in plant and food-science. Many clinical applications have been developed to analyze the complexity of biofluids, which are being addressed with new instrumentation, automization, and data processing. Additionally, the newly developed field of immunopeptidomics is showing promise for cancer therapies. In conclusion, peptidomics will continue delivering important information in classical fields like neuropeptides and peptide hormones, benefiting from improvements in state-of-the-art technologies. Moreover, new directions of research such as immunopeptidomics will further complement classical omics technologies and may become routine clinical procedures. Taken together, discoveries of new substances, networks, and applications of peptides can be expected in different disciplines.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages485-498
Number of pages14
DOIs
StatePublished - 2024

Publication series

NameMethods in Molecular Biology
Volume2758
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Future perspectives
  • Outlook
  • Peptidomics

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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