CT colonography: Perforation rates and potential radiation risks

A. Berrington de Gonzalez, Kwang Pyo Kim, Judy Yee

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations


Computed tomographic colonography (CTC) has emerged as an alternative screening tool for colorectal cancer due to the potential to provide good efficacy combined with greater acceptability than optical colonoscopy or fecal occult blood testing. However, some organizations have raised concerns about the potential harms, including perforation rates and radiation-related cancer risks, and have not recommended that it currently be used as a screening tool in the general population in the US. In this article the authors review the current evidence for these potential harms from CTC and compare them to the potential harms from the alternatives including colonoscopy and double-contrast barium enema.

Original languageEnglish (US)
Pages (from-to)279-291
Number of pages13
JournalGastrointestinal Endoscopy Clinics of North America
Issue number2
StatePublished - Apr 2010
Externally publishedYes


  • Colonography
  • Colorectal cancer
  • Computed tomography
  • Perforation
  • Radiation
  • Risk
  • Screening

ASJC Scopus subject areas

  • Gastroenterology


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