Cryptococcal Disease in HIV-Infected Children

Carol Kao; David L. Goldman

doi:10.1007/s11908-016-0534-9

Cryptococcal Disease in HIV-Infected Children

Carol Kao, David L. Goldman

Pediatrics

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

Cryptococcus neoformans is an encapsulated fungal pathogen that is remarkable for its tendency to cause meningoencephalitis, especially in patients with AIDS. While disease is less common in children than adults, it remains an important cause of morbidity and mortality among HIV-infected children without access to anti-retroviral therapy. This review highlights recent insights into both the biology and treatment of cryptococcosis with a special emphasis on the pediatric literature.

Original language	English (US)
Article number	27
Journal	Current Infectious Disease Reports
Volume	18
Issue number	9
DOIs	https://doi.org/10.1007/s11908-016-0534-9
State	Published - Sep 1 2016

Keywords

AIDS
Cryptococcosis
Immune reconstitution inflammatory syndrome (IRIS)
Increased intracranial pressure
Meningoencephalitis

ASJC Scopus subject areas

Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s11908-016-0534-9

Cite this

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abstract = "Cryptococcus neoformans is an encapsulated fungal pathogen that is remarkable for its tendency to cause meningoencephalitis, especially in patients with AIDS. While disease is less common in children than adults, it remains an important cause of morbidity and mortality among HIV-infected children without access to anti-retroviral therapy. This review highlights recent insights into both the biology and treatment of cryptococcosis with a special emphasis on the pediatric literature.",

keywords = "AIDS, Cryptococcosis, Immune reconstitution inflammatory syndrome (IRIS), Increased intracranial pressure, Meningoencephalitis",

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AU - Goldman, David L.

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N2 - Cryptococcus neoformans is an encapsulated fungal pathogen that is remarkable for its tendency to cause meningoencephalitis, especially in patients with AIDS. While disease is less common in children than adults, it remains an important cause of morbidity and mortality among HIV-infected children without access to anti-retroviral therapy. This review highlights recent insights into both the biology and treatment of cryptococcosis with a special emphasis on the pediatric literature.

AB - Cryptococcus neoformans is an encapsulated fungal pathogen that is remarkable for its tendency to cause meningoencephalitis, especially in patients with AIDS. While disease is less common in children than adults, it remains an important cause of morbidity and mortality among HIV-infected children without access to anti-retroviral therapy. This review highlights recent insights into both the biology and treatment of cryptococcosis with a special emphasis on the pediatric literature.

KW - AIDS

KW - Cryptococcosis

KW - Immune reconstitution inflammatory syndrome (IRIS)

KW - Increased intracranial pressure

KW - Meningoencephalitis

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Cryptococcal Disease in HIV-Infected Children

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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