Cross-Cultural Comparisons of Subjective Cognitive Complaints in a Diverse Primary Care Population

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Background: Very few studies have explored the utility of subjective cognitive complaints (SCCs) in primary care settings. Objective: We aim to investigate associations between SCCs (item-level), objective cognitive function (across domains and global), and mood in a diverse primary care population, including subjects with mild cognitive impairment. Methods: We studied 199 (75.9% females; 57.8% Hispanics; 42.2% African Americans) older adults (mean age 72.5 years) with memory concerns at a primary care clinic. A five-item SCC questionnaire, and objective cognitive assessments, including the Montreal Cognitive Assessment (MoCA) and the Geriatric Depression Scale, were administered. Results: Logistic regression analyses showed associations between SCC score and depressive symptoms. A memory-specific ('memory worsening') SCC predicted scores on the MoCA (p = 0.005) in Hispanics. Conclusion: SCCs are strongly linked to depressive symptoms in African Americans and Hispanics in a primary care setting; a specific type of SCC is related to global cognitive function in Hispanics.

Original languageEnglish (US)
Pages (from-to)563-574
Number of pages12
JournalAdvances in Alzheimer's Disease
StatePublished - 2024


  • Cognitive function
  • cross-sectional
  • depressive symptoms
  • primary care
  • subjective health complaint
  • underserved populations

ASJC Scopus subject areas

  • Clinical Neurology


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