Control of ciliary motility: A unifying hypothesis

Peter Satir, Charles Guerra

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Ciliary motility in ciliates such as Paramecium or Tetrahymena is the mechanism by which cellular behaviour is regulated and on which survival depends. As a consequence, protozoan cilia have elaborate sensing systems built into them, probably by intraciliary transport (ICT-orthologous to intraflagellar transport). As a response to stimuli, 2nd messenger concentration around the axoneme increases. A unifying hypothesis suggests that for rapid responses the 2nd messengers act on axonemal dynein to change the rates of doublet sliding, which in turn affects ciliary parameters that control behaviour.

Original languageEnglish (US)
Pages (from-to)410-415
Number of pages6
JournalEuropean Journal of Protistology
Issue number4
StatePublished - Dec 2003


  • Centrin
  • Cilia
  • Dynein
  • Intraciliary transport
  • cAMP

ASJC Scopus subject areas

  • Microbiology


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