Connecting genes to brain in the autism spectrum disorders

Brett S. Abrahams; Daniel H. Geschwind

doi:10.1001/archneurol.2010.47

Connecting genes to brain in the autism spectrum disorders

Brett S. Abrahams, Daniel H. Geschwind

Research output: Contribution to journal › Review article › peer-review

143 Scopus citations

Abstract

The autism spectrum disorders (ASDs) are a complex group of neuropsychiatric conditions involving language, social communication, and mental flexibility. Here, we attempt to place recent genetic advances within a developmental and anatomical context. Recent progress in identifying ASD candidate genes supports involvement of multiple brain regions, including the frontal lobes, anterior temporal lobes, caudate, and cerebellum. Understanding genetic data within an anatomical context will be critical to explain how individual risk factors operate to shape phenotypic presentation in patients.

Original language	English (US)
Pages (from-to)	395-399
Number of pages	5
Journal	Archives of Neurology
Volume	67
Issue number	4
DOIs	https://doi.org/10.1001/archneurol.2010.47
State	Published - Apr 2010
Externally published	Yes

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Clinical Neurology

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10.1001/archneurol.2010.47

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Connecting genes to brain in the autism spectrum disorders

Abstract

ASJC Scopus subject areas

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