Computed Sonography: Requiem to Echogenicity Assessment?

Isaac Blickstein, Michelle Smith-Levitin, Edith Gwewitsch, Jane Streltzhoff, Ran D. Goldman, Frank A. Chervenak

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


We studied the influence of changes in gain settings, log compression, persistence, preprocessing, and postprocessing on image density in the fetal liver model. Each parameter was studied while the others were held constant. The image density was objectively measured by electrooptical transmission densitometry using a transparent film output. Neither the persistence nor the preprocessing levels significantly changed image density. Postprocessing of sonographic images produced significant differences (p < 0.02) in mean image density of most of the various postprocessing curves and is a serious confounder of tissue echogenicity assessment. The data reconfirmed that there is a linear relationship (r = −0.94 to −0.997) between image density and gain setting. However, each log compression setting significantly changed (p < 0.0000001) this relationship, obviating possible image density calibration. Our data suggest that manipulation of image parameters by computed sonographic technology obviates accurate echogenicity assessment.

Original languageEnglish (US)
Pages (from-to)244-248
Number of pages5
JournalGynecologic and Obstetric Investigation
Issue number4
StatePublished - Jan 1 1997
Externally publishedYes


  • Echogenicity assessment
  • Fetal liver, computed sonography
  • Image density
  • Ultrasound

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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