Comparative protein structure modelling

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


A prerequisite to understand cell functioning on the system level is the knowledge of three-dimensional protein structures that mediate biochemical inter actions. The explosion in the number of available gene sequences set the stage for the next step in genome scale projects, to obtain three dimensional structures for each protein. To achieve this ambitious goal, the costly and slow structure determi nation experiments are boosted with theoretical approaches. The current state and recent advances in structure modelling approaches are reviewed here, with special emphasis on comparative structure modelling techniques

Original languageEnglish (US)
Title of host publicationFrom Protein Structure to Function with Bioinformatics
PublisherSpringer Netherlands
Number of pages34
ISBN (Print)9781402090578
StatePublished - Dec 1 2009

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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