Cognitive deficits and psychopathology in elderly schizophrenic patients

Jean Pierre Lindenmayer, Arnaldo E. Negrón, Shilpa Shah, Robert Lowinger, Gary Kennedy, Nigel Bark, Ruth Hyman

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The authors investigated the syndromal and cognitive profiles of 25 DSM- III-R older schizophrenic inpatients with continuous acute psychotic symptoms and compared them with 20 younger schizophrenic patients by means of a multidimensional assessment battery. Subjects were medically well and without neurological comorbidity and were comparable in length of current hospitalization and medication regimens. There were no significant differences between the two groups on various symptom rating scores or on neurological variables. The older group's mean scores for various cognitive measures did not reach the value for senile dementia. They also scored significantly better on a memory test and on formal cognitive functions. These findings support the notion of a stable encephalopathy, rather than a dementia-like process, underlying the course of the illness. Authors discussed limitations and implications of these findings.

Original languageEnglish (US)
Pages (from-to)31-42
Number of pages12
JournalAmerican Journal of Geriatric Psychiatry
Issue number1
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health


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