Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder

Amy Farabaugh; Joseph J. Locascio; Liang Yap; John Growdon; Maurizio Fava; Christine Crawford; John Matthews; Jesse McCutchen; Jacqueline Buchin; Joel Pava; Jonathan E. Alpert

doi:10.1176/appi.psy.51.2.124

Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder

Amy Farabaugh, Joseph J. Locascio, Liang Yap, John Growdon, Maurizio Fava, Christine Crawford, John Matthews, Jesse McCutchen, Jacqueline Buchin, Joel Pava, Jonathan E. Alpert

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Background: Depression has been recognized as a common feature of Parkinson's disease (PD), and is the most prevalent psychiatric disorder in PD patients. Objective: The authors sought to determine whether cognitive-behavioral therapy (CBT) is effective in the treatment of depression within the context of PD (dPD). Method: The authors enrolled 8 depressed PD patients into an open treatment study of 12 weeks of individual CBT treatment. Results: There was a significant linear decrease in mean Hamilton Rating Scale for Depression (17-item) scores over Weeks 0 to 12, and 57% of patients (4/7) met criteria for remission at endpoint. Conclusion: This uncontrolled study suggests that CBT may be effective in treating dPD and may be an alternative or adjunct to pharmacological treatment.

Original language	English (US)
Pages (from-to)	124-129
Number of pages	6
Journal	Psychosomatics
Volume	51
Issue number	2
DOIs	https://doi.org/10.1176/appi.psy.51.2.124
State	Published - Jan 1 2010
Externally published	Yes

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Applied Psychology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1176/appi.psy.51.2.124

Cite this

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title = "Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder",

abstract = "Background: Depression has been recognized as a common feature of Parkinson's disease (PD), and is the most prevalent psychiatric disorder in PD patients. Objective: The authors sought to determine whether cognitive-behavioral therapy (CBT) is effective in the treatment of depression within the context of PD (dPD). Method: The authors enrolled 8 depressed PD patients into an open treatment study of 12 weeks of individual CBT treatment. Results: There was a significant linear decrease in mean Hamilton Rating Scale for Depression (17-item) scores over Weeks 0 to 12, and 57% of patients (4/7) met criteria for remission at endpoint. Conclusion: This uncontrolled study suggests that CBT may be effective in treating dPD and may be an alternative or adjunct to pharmacological treatment.",

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T1 - Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder

AU - Farabaugh, Amy

AU - Locascio, Joseph J.

AU - Yap, Liang

AU - Growdon, John

AU - Fava, Maurizio

AU - Crawford, Christine

AU - Matthews, John

AU - McCutchen, Jesse

AU - Buchin, Jacqueline

AU - Pava, Joel

AU - Alpert, Jonathan E.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Background: Depression has been recognized as a common feature of Parkinson's disease (PD), and is the most prevalent psychiatric disorder in PD patients. Objective: The authors sought to determine whether cognitive-behavioral therapy (CBT) is effective in the treatment of depression within the context of PD (dPD). Method: The authors enrolled 8 depressed PD patients into an open treatment study of 12 weeks of individual CBT treatment. Results: There was a significant linear decrease in mean Hamilton Rating Scale for Depression (17-item) scores over Weeks 0 to 12, and 57% of patients (4/7) met criteria for remission at endpoint. Conclusion: This uncontrolled study suggests that CBT may be effective in treating dPD and may be an alternative or adjunct to pharmacological treatment.

AB - Background: Depression has been recognized as a common feature of Parkinson's disease (PD), and is the most prevalent psychiatric disorder in PD patients. Objective: The authors sought to determine whether cognitive-behavioral therapy (CBT) is effective in the treatment of depression within the context of PD (dPD). Method: The authors enrolled 8 depressed PD patients into an open treatment study of 12 weeks of individual CBT treatment. Results: There was a significant linear decrease in mean Hamilton Rating Scale for Depression (17-item) scores over Weeks 0 to 12, and 57% of patients (4/7) met criteria for remission at endpoint. Conclusion: This uncontrolled study suggests that CBT may be effective in treating dPD and may be an alternative or adjunct to pharmacological treatment.

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Cognitive-behavioral therapy for patients with Parkinson's disease and comorbid major depressive disorder

Abstract

ASJC Scopus subject areas

UN SDGs

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