TY - JOUR
T1 - Clonal chromosome aberrations with monosomy of chromosome 8 in a case of grade III chondrosarcoma
AU - Ptaszynski, Konrad
AU - Ramesh, K. H.
AU - Cannizzaro, Linda A.
PY - 1997/8/1
Y1 - 1997/8/1
N2 - We report cytogenetic findings in a case of grade III chondrosarcoma. Complex clonal chromosome aberrations including monosomy of chromosomes 4, 8, 13, and a consistent t(5;14)(q23;p12) were observed in all cells. There were no structural or numerical anomalies involving chromosome 12. The complexity of the chromosome aberrations reflect the advanced stage of this chondrosarcoma; we suggest a possible involvement of the EXT1 gene located on chromosome 8.
AB - We report cytogenetic findings in a case of grade III chondrosarcoma. Complex clonal chromosome aberrations including monosomy of chromosomes 4, 8, 13, and a consistent t(5;14)(q23;p12) were observed in all cells. There were no structural or numerical anomalies involving chromosome 12. The complexity of the chromosome aberrations reflect the advanced stage of this chondrosarcoma; we suggest a possible involvement of the EXT1 gene located on chromosome 8.
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U2 - 10.1016/S0165-4608(96)00360-3
DO - 10.1016/S0165-4608(96)00360-3
M3 - Article
C2 - 9242219
AN - SCOPUS:0031215017
SN - 0165-4608
VL - 97
SP - 60
EP - 63
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 1
ER -
