Choline supplements: An update

Urna Kansakar; Valentina Trimarco; Pasquale Mone; Fahimeh Varzideh; Angela Lombardi; Gaetano Santulli

doi:10.3389/fendo.2023.1148166

Choline supplements: An update

Urna Kansakar, Valentina Trimarco, Pasquale Mone, Fahimeh Varzideh, Angela Lombardi, Gaetano Santulli

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C₈H₂₀NO₆P), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic compounds and precursors of acetylcholine. Extensively used as food supplements, they have been shown to represent an effective strategy for boosting memory and enhancing cognitive function.

Original language	English (US)
Article number	1148166
Journal	Frontiers in Endocrinology
Volume	14
DOIs	https://doi.org/10.3389/fendo.2023.1148166
State	Published - 2023
Externally published	Yes

Keywords

GPC
choline
choline alfoscerate
choline bitartrate
choline supplementation
cognitive dysfunction
lecithin
supplements

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3389/fendo.2023.1148166

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title = "Choline supplements: An update",

abstract = "In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C8H20NO6P), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic compounds and precursors of acetylcholine. Extensively used as food supplements, they have been shown to represent an effective strategy for boosting memory and enhancing cognitive function.",

keywords = "GPC, choline, choline alfoscerate, choline bitartrate, choline supplementation, cognitive dysfunction, lecithin, supplements",

author = "Urna Kansakar and Valentina Trimarco and Pasquale Mone and Fahimeh Varzideh and Angela Lombardi and Gaetano Santulli",

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year = "2023",

doi = "10.3389/fendo.2023.1148166",

language = "English (US)",

volume = "14",

journal = "Frontiers in Endocrinology",

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TY - JOUR

T1 - Choline supplements

T2 - An update

AU - Kansakar, Urna

AU - Trimarco, Valentina

AU - Mone, Pasquale

AU - Varzideh, Fahimeh

AU - Lombardi, Angela

AU - Santulli, Gaetano

PY - 2023

Y1 - 2023

N2 - In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C8H20NO6P), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic compounds and precursors of acetylcholine. Extensively used as food supplements, they have been shown to represent an effective strategy for boosting memory and enhancing cognitive function.

AB - In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C8H20NO6P), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic compounds and precursors of acetylcholine. Extensively used as food supplements, they have been shown to represent an effective strategy for boosting memory and enhancing cognitive function.

KW - GPC

KW - choline

KW - choline alfoscerate

KW - choline bitartrate

KW - choline supplementation

KW - cognitive dysfunction

KW - lecithin

KW - supplements

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DO - 10.3389/fendo.2023.1148166

M3 - Review article

AN - SCOPUS:85150518763

SN - 1664-2392

VL - 14

JO - Frontiers in Endocrinology

JF - Frontiers in Endocrinology

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ER -

Choline supplements: An update

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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