Abstract
Using a cDNA probe for the mitochondrially encoded third subunit of cytochrome c oxidase (COIII) we found a progressive increase in the number of mitochondrial DNA molecules in specific human tissues during normal fetal development. The data indicate that the tissue, rather than the final number of mitochondrial genomes, apparently plays a dominant role in determining the gestational stage at which the adult complement of this DNA is established.
Original language | English (US) |
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Pages (from-to) | 54-59 |
Number of pages | 6 |
Journal | Experimental Cell Research |
Volume | 186 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1990 |
ASJC Scopus subject areas
- Cell Biology