Central venous catheter infections: Identification of high-risk patients

Satheesh Nair, Ravi Ramaswamy, Marilou Corpuz

Research output: Contribution to journalArticlepeer-review


Infection of central venous catheters (CVCs) is an independent risk factor for increased mortality and morbidity. As a method to prevent infection, prescheduled changing of all catheters to a new site is costly and is associated with procedure-related complications. The aim of the study was to analyze various patient-related parameters that can place patients at risk of acquiring catheter infection and to identify the subset of patients at highest risk of developing catheter infection, so that prescheduled relocation of catheters to a new site is limited to them. A retrospective review of 300 patients with CVC was conducted to identify the patients who had evidence of catheter infection. The patients who did not develop infection were taken as control. The potential risk factors were compared between the groups. The χ2 test and Student's t test were used, when appropriate, to test the statistical significance. A serum albumin level of <25 g/L on admission, a fall in serum albumin of >9 g/L, and prolonged (>12 days) use of a catheter were also associated with increased risk of CVC infection. The age, past medical history, immunocompromised states, concurrent antibiotic usage, or infusion of nutritional substances through the CVC were not found to have any influence on the infection rate. Serum albumin on admission combined with serial measurements can be used as an inexpensive but reliable guide to identify the patients most likely to develop catheter infection. It would be cost effective and safer if relocation of catheters at predetermined intervals is limited to such high- risk patients.

Original languageEnglish (US)
Pages (from-to)334-339
Number of pages6
JournalInfectious Diseases in Clinical Practice
Issue number5
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


Dive into the research topics of 'Central venous catheter infections: Identification of high-risk patients'. Together they form a unique fingerprint.

Cite this