Breaking Up Isn't Hard to Do: Isolating Cell-free DNA Fragments in Osteosarcoma

Daniel A. Weiser, Masanori Hayashi, Mark A. Applebaum

Research output: Contribution to journalArticlepeer-review

Abstract

The novel use of blood-based biospecimens from a retrospective cohort of 50 patients with osteosarcoma was recently studied. The potential clinical utility of sorting cell-free DNA by fragment size was defined, with shorter tumor-specific DNA enrichment providing prognostic value and allowing for streamlined molecular profiling of circulating tumor material.

Original languageEnglish (US)
Pages (from-to)2017-2019
Number of pages3
JournalClinical Cancer Research
Volume29
Issue number11
DOIs
StatePublished - Jun 1 2023

ASJC Scopus subject areas

  • General Medicine

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