Biomaterials in Regenerative Medicine and the Immune System

Laura Santambrogio

Research output: Book/ReportBook

9 Scopus citations


The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components. As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.

Original languageEnglish (US)
PublisherSpringer International Publishing
Number of pages280
ISBN (Print)9783319180458, 9783319180441
StatePublished - Sep 4 2015

ASJC Scopus subject areas

  • General Engineering
  • General Materials Science
  • General Medicine
  • General Immunology and Microbiology
  • General Biochemistry, Genetics and Molecular Biology


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