Bile pigment composition and hepatic UDP-glucuronyl transferase activity in the fetal and adult dogfish shark, Squalus acanthias

N. Roy Chowdhury; J. Roy Chowdhury; Irwin M. Arias

doi:10.1016/0305-0491(82)90091-8

Bile pigment composition and hepatic UDP-glucuronyl transferase activity in the fetal and adult dogfish shark, Squalus acanthias

N. Roy Chowdhury, J. Roy Chowdhury, Irwin M. Arias

Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

1. 1. Bile pigments from adult and fetal spiny dogfish (Squalus acanthias) were separated and quantitated by high pressure liquid chromatography. 2. 2. In order of relative abundance, bilirubin monoglucuronide, unconjugated bilirubin, bilirubin diglucuronide and bilirubin monoglucoside were present in adult bile and in fetal bile and meconium. 3. 3. All bile pigments were of IX_α configuration. 4. 4. Specific hepatic microsomal UDP-glucuronate glucuronosyl transferase activity towards bilirubin and p-nitrophenol were comparable in fetal and adult dogfish.

Original language	English (US)
Pages (from-to)	651-653
Number of pages	3
Journal	Comparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume	73
Issue number	3
DOIs	https://doi.org/10.1016/0305-0491(82)90091-8
State	Published - 1982

ASJC Scopus subject areas

Biochemistry
Physiology
Molecular Biology

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@article{f5de142d45794924b38275210e9f36e3,

title = "Bile pigment composition and hepatic UDP-glucuronyl transferase activity in the fetal and adult dogfish shark, Squalus acanthias",

abstract = "1. 1. Bile pigments from adult and fetal spiny dogfish (Squalus acanthias) were separated and quantitated by high pressure liquid chromatography. 2. 2. In order of relative abundance, bilirubin monoglucuronide, unconjugated bilirubin, bilirubin diglucuronide and bilirubin monoglucoside were present in adult bile and in fetal bile and meconium. 3. 3. All bile pigments were of IXα configuration. 4. 4. Specific hepatic microsomal UDP-glucuronate glucuronosyl transferase activity towards bilirubin and p-nitrophenol were comparable in fetal and adult dogfish.",

author = "Chowdhury, {N. Roy} and Chowdhury, {J. Roy} and Arias, {Irwin M.}",

note = "Funding Information: In the present study, we separated and quantitated bilirubin and its conjugates in the bile of the adult * Supported by the National Institutes of Health grant: AM 02019, AM 17702. Dr. J. Roy Chowdhury is a recipient of a Research Career Development Award of the National Institutes of Health AM 01016.",

year = "1982",

doi = "10.1016/0305-0491(82)90091-8",

language = "English (US)",

volume = "73",

pages = "651--653",

journal = "Comparative Biochemistry and Physiology -- Part B: Biochemistry and",

issn = "0305-0491",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Bile pigment composition and hepatic UDP-glucuronyl transferase activity in the fetal and adult dogfish shark, Squalus acanthias

AU - Chowdhury, N. Roy

AU - Chowdhury, J. Roy

AU - Arias, Irwin M.

N1 - Funding Information: In the present study, we separated and quantitated bilirubin and its conjugates in the bile of the adult * Supported by the National Institutes of Health grant: AM 02019, AM 17702. Dr. J. Roy Chowdhury is a recipient of a Research Career Development Award of the National Institutes of Health AM 01016.

PY - 1982

Y1 - 1982

N2 - 1. 1. Bile pigments from adult and fetal spiny dogfish (Squalus acanthias) were separated and quantitated by high pressure liquid chromatography. 2. 2. In order of relative abundance, bilirubin monoglucuronide, unconjugated bilirubin, bilirubin diglucuronide and bilirubin monoglucoside were present in adult bile and in fetal bile and meconium. 3. 3. All bile pigments were of IXα configuration. 4. 4. Specific hepatic microsomal UDP-glucuronate glucuronosyl transferase activity towards bilirubin and p-nitrophenol were comparable in fetal and adult dogfish.

AB - 1. 1. Bile pigments from adult and fetal spiny dogfish (Squalus acanthias) were separated and quantitated by high pressure liquid chromatography. 2. 2. In order of relative abundance, bilirubin monoglucuronide, unconjugated bilirubin, bilirubin diglucuronide and bilirubin monoglucoside were present in adult bile and in fetal bile and meconium. 3. 3. All bile pigments were of IXα configuration. 4. 4. Specific hepatic microsomal UDP-glucuronate glucuronosyl transferase activity towards bilirubin and p-nitrophenol were comparable in fetal and adult dogfish.

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U2 - 10.1016/0305-0491(82)90091-8

DO - 10.1016/0305-0491(82)90091-8

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AN - SCOPUS:0020456798

SN - 0305-0491

VL - 73

SP - 651

EP - 653

JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and

JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and

IS - 3

ER -

Bile pigment composition and hepatic UDP-glucuronyl transferase activity in the fetal and adult dogfish shark, Squalus acanthias

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