Bending of short DNA helices

Alexander Vologodskii, Quan Du, Maxim Frank-Kamenetskii

Research output: Contribution to journalComment/debatepeer-review

23 Scopus citations

Abstract

In their recent Science paper, Vafabakhsh and Ha claim that DNA duplexes at the range of 100 bp experience anomalous flexibility, much greater than the flexibility of large DNA molecules. 1 However, careful reevaluation of their data leads to the conclusion that the presented data do not warrant the authors' claim.

Original languageEnglish (US)
JournalArtificial DNA: PNA and XNA
Volume4
Issue number1
DOIs
StatePublished - Mar 2013

Keywords

  • DNA bending flexibility
  • DNA extreme bendability
  • DNA minicircles
  • DNA sticky ends
  • Single-molecule data

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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