Bending of short DNA helices

Alexander Vologodskii; Quan Du; Maxim Frank-Kamenetskii

doi:10.4161/adna.23892

Bending of short DNA helices

Alexander Vologodskii, Quan Du, Maxim Frank-Kamenetskii

Research output: Contribution to journal › Comment/debate › peer-review

22 Scopus citations

Abstract

In their recent Science paper, Vafabakhsh and Ha claim that DNA duplexes at the range of 100 bp experience anomalous flexibility, much greater than the flexibility of large DNA molecules. 1 However, careful reevaluation of their data leads to the conclusion that the presented data do not warrant the authors' claim.

Original language	English (US)
Journal	Artificial DNA: PNA and XNA
Volume	4
Issue number	1
DOIs	https://doi.org/10.4161/adna.23892
State	Published - Mar 2013
Externally published	Yes

Keywords

DNA bending flexibility
DNA extreme bendability
DNA minicircles
DNA sticky ends
Single-molecule data

ASJC Scopus subject areas

Biochemistry
Organic Chemistry

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10.4161/adna.23892

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title = "Bending of short DNA helices",

abstract = "In their recent Science paper, Vafabakhsh and Ha claim that DNA duplexes at the range of 100 bp experience anomalous flexibility, much greater than the flexibility of large DNA molecules. 1 However, careful reevaluation of their data leads to the conclusion that the presented data do not warrant the authors' claim.",

keywords = "DNA bending flexibility, DNA extreme bendability, DNA minicircles, DNA sticky ends, Single-molecule data",

author = "Alexander Vologodskii and Quan Du and Maxim Frank-Kamenetskii",

year = "2013",

month = mar,

doi = "10.4161/adna.23892",

language = "English (US)",

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journal = "Artificial DNA: PNA and XNA",

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AU - Vologodskii, Alexander

AU - Du, Quan

AU - Frank-Kamenetskii, Maxim

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N2 - In their recent Science paper, Vafabakhsh and Ha claim that DNA duplexes at the range of 100 bp experience anomalous flexibility, much greater than the flexibility of large DNA molecules. 1 However, careful reevaluation of their data leads to the conclusion that the presented data do not warrant the authors' claim.

AB - In their recent Science paper, Vafabakhsh and Ha claim that DNA duplexes at the range of 100 bp experience anomalous flexibility, much greater than the flexibility of large DNA molecules. 1 However, careful reevaluation of their data leads to the conclusion that the presented data do not warrant the authors' claim.

KW - DNA bending flexibility

KW - DNA extreme bendability

KW - DNA minicircles

KW - DNA sticky ends

KW - Single-molecule data

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DO - 10.4161/adna.23892

M3 - Comment/debate

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JO - Artificial DNA: PNA and XNA

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Bending of short DNA helices

Abstract

Keywords

ASJC Scopus subject areas

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