Abstract
The B-raf gene was localized to human chromosome region 7p11-7qter by Southern blot analysis of its segregation in a panel of rodent-human hybrids, using a B-raf cDNA clone. Chromosomal in situ hybridization refined the localization to 7q33-36. Analysis of genomic B-raf clones identified a B-raf pseudogene in addition to the active gene. Based on the chromosomal mapping data we conclude that the pseudogene is located near the active gene.
Original language | English (US) |
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Pages (from-to) | 795-799 |
Number of pages | 5 |
Journal | Oncogene |
Volume | 7 |
Issue number | 4 |
State | Published - Jan 1 1992 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research