Azidothymidine(AZT)‐induced siderosis

Simeon Pollack, Janet Weaver

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Azidothymidine(AZT) interferes with heme synthesis. This should upregulate the synthesis of transferrin receptors and increase the amount of iron taken up by the cell. We found a 50% increase in the iron content of liver and a 20% increase in the iron content of macrophages in AZT‐treated mice.

Original languageEnglish (US)
Pages (from-to)230-233
Number of pages4
JournalAmerican Journal of Hematology
Issue number3
StatePublished - Jul 1993


  • AIDS
  • iron
  • liver
  • macrophage

ASJC Scopus subject areas

  • Hematology


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