Statins are the mainstay of therapy in coronary artery disease and hypercholesterolemia. Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitor that is taken once daily. It has been shown to considerably reduce cardiovascular mortality events. Recently, several trials have demonstrated that atorvastatin has pleiotropic effects beyond its lipid-lowering capacities. Atorvastatin is especially beneficial in diabetics for stroke prevention and improving cardiovascular mortality risk.
- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
- Cerebrovascular accident
- Coronary heart disease
- Diabetes mellitus
ASJC Scopus subject areas
- Molecular Medicine
- Cardiology and Cardiovascular Medicine