Abstract
Statins are the mainstay of therapy in coronary artery disease and hypercholesterolemia. Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitor that is taken once daily. It has been shown to considerably reduce cardiovascular mortality events. Recently, several trials have demonstrated that atorvastatin has pleiotropic effects beyond its lipid-lowering capacities. Atorvastatin is especially beneficial in diabetics for stroke prevention and improving cardiovascular mortality risk.
Original language | English (US) |
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Pages (from-to) | 527-533 |
Number of pages | 7 |
Journal | Future Cardiology |
Volume | 2 |
Issue number | 5 |
DOIs | |
State | Published - Sep 1 2006 |
Keywords
- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
- Atorvastatin
- Cerebrovascular accident
- Coronary heart disease
- Diabetes mellitus
ASJC Scopus subject areas
- Molecular Medicine
- Cardiology and Cardiovascular Medicine