Asymptomatic Demyelinated Plaque

Nitya R. Ghatak; Asao Hirano; Hugo Lijtmaer; Harry M. Zimmerman

doi:10.1001/archneur.1974.00490360060012

Asymptomatic Demyelinated Plaque

Nitya R. Ghatak, Asao Hirano, Hugo Lijtmaer, Harry M. Zimmerman

Pathology

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

A clinically silent multiple sclerosis (MS) plaque in the midcervical spinal cord was found unexpectedly at autopsy in a 66-year-old man who died of bronchogenic carcinoma. The patient's history revealed a transient episode of neurological symptoms compatible with an attack of MS more than 30 years prior to death, with no appreciable residual deficits. The discrete anatomical location of this plaque with well-preserved axons emphasizes that the retention of functional integrity of demyelinated axons may be an important factor underlying the poor clinicopathologic correlation in MS.

Original language	English (US)
Pages (from-to)	484-486
Number of pages	3
Journal	Archives of Neurology
Volume	30
Issue number	6
DOIs	https://doi.org/10.1001/archneur.1974.00490360060012
State	Published - Jun 1974

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Clinical Neurology

Access to Document

10.1001/archneur.1974.00490360060012

Cite this

@article{5500df170f15474c8b2183e06871d4e9,

title = "Asymptomatic Demyelinated Plaque",

abstract = "A clinically silent multiple sclerosis (MS) plaque in the midcervical spinal cord was found unexpectedly at autopsy in a 66-year-old man who died of bronchogenic carcinoma. The patient's history revealed a transient episode of neurological symptoms compatible with an attack of MS more than 30 years prior to death, with no appreciable residual deficits. The discrete anatomical location of this plaque with well-preserved axons emphasizes that the retention of functional integrity of demyelinated axons may be an important factor underlying the poor clinicopathologic correlation in MS.",

author = "Ghatak, {Nitya R.} and Asao Hirano and Hugo Lijtmaer and Zimmerman, {Harry M.}",

year = "1974",

month = jun,

doi = "10.1001/archneur.1974.00490360060012",

language = "English (US)",

volume = "30",

pages = "484--486",

journal = "Archives of Neurology",

issn = "0003-9942",

publisher = "American Medical Association",

number = "6",

}

TY - JOUR

T1 - Asymptomatic Demyelinated Plaque

AU - Ghatak, Nitya R.

AU - Hirano, Asao

AU - Lijtmaer, Hugo

AU - Zimmerman, Harry M.

PY - 1974/6

Y1 - 1974/6

N2 - A clinically silent multiple sclerosis (MS) plaque in the midcervical spinal cord was found unexpectedly at autopsy in a 66-year-old man who died of bronchogenic carcinoma. The patient's history revealed a transient episode of neurological symptoms compatible with an attack of MS more than 30 years prior to death, with no appreciable residual deficits. The discrete anatomical location of this plaque with well-preserved axons emphasizes that the retention of functional integrity of demyelinated axons may be an important factor underlying the poor clinicopathologic correlation in MS.

AB - A clinically silent multiple sclerosis (MS) plaque in the midcervical spinal cord was found unexpectedly at autopsy in a 66-year-old man who died of bronchogenic carcinoma. The patient's history revealed a transient episode of neurological symptoms compatible with an attack of MS more than 30 years prior to death, with no appreciable residual deficits. The discrete anatomical location of this plaque with well-preserved axons emphasizes that the retention of functional integrity of demyelinated axons may be an important factor underlying the poor clinicopathologic correlation in MS.

UR - http://www.scopus.com/inward/record.url?scp=0016161013&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016161013&partnerID=8YFLogxK

U2 - 10.1001/archneur.1974.00490360060012

DO - 10.1001/archneur.1974.00490360060012

M3 - Article

C2 - 4827065

AN - SCOPUS:0016161013

SN - 0003-9942

VL - 30

SP - 484

EP - 486

JO - Archives of Neurology

JF - Archives of Neurology

IS - 6

ER -

Asymptomatic Demyelinated Plaque

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this