Asymptomatic Demyelinated Plaque

Nitya R. Ghatak, Asao Hirano, Hugo Lijtmaer, Harry M. Zimmerman

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


A clinically silent multiple sclerosis (MS) plaque in the midcervical spinal cord was found unexpectedly at autopsy in a 66-year-old man who died of bronchogenic carcinoma. The patient's history revealed a transient episode of neurological symptoms compatible with an attack of MS more than 30 years prior to death, with no appreciable residual deficits. The discrete anatomical location of this plaque with well-preserved axons emphasizes that the retention of functional integrity of demyelinated axons may be an important factor underlying the poor clinicopathologic correlation in MS.

Original languageEnglish (US)
Pages (from-to)484-486
Number of pages3
JournalArchives of Neurology
Issue number6
StatePublished - Jun 1974

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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