TY - JOUR
T1 - Association between respiratory disease and stress urinary incontinence
T2 - An analysis of the 2015−2020 National Health and Nutrition Examination Survey
AU - Zhu, Michael
AU - Sim, Jasper
AU - Okada, Chihiro
AU - Kim, Joseph
AU - Abraham, Nitya
N1 - Publisher Copyright:
© 2023 Wiley Periodicals LLC.
PY - 2023/8
Y1 - 2023/8
N2 - Introduction: There is a logical association between chronic obstructive pulmonary disease (COPD) or asthma with stress urinary incontinence (SUI), given the propensity for coughing which increases intra-abdominal pressure. However, there are few studies examining the association between COPD or asthma and specifically SUI. We aimed to utilize the National Health and Nutrition Examination Survey (NHANES) data from 2015 to 2020 to measure the association between respiratory diseases like COPD and asthma with SUI. Methods: Data was collected from NHANES, a database representative of the United States population. Participants were included if they were female, older than 20 years, and completed the incontinence survey question. Self-reported history of asthma and COPD diagnosis from a physician, as well as history of incontinence associated with activities such as coughing, lifting, or exercise, were collected. Characteristics of participants were compared using χ2 and Student t-tests. Multivariable logistic regression was performed using a multimodel approach to adjust for sociodemographic and health-related covariates. Results: A total of 9059 women were included in this study. 42.13% reported an episode of SUI in the past year, 6.29% had a COPD diagnosis, and 11.86% had an asthma diagnosis. In the unadjusted analysis, participants with COPD were more likely to report SUI (odds ratio [OR] 3.42, 95% confidence interval [CI] 2.13−5.49, p < 0.001); this association persisted on multivariable analysis (OR 2.87, 95% CI 1.46−5.60, p = 0.003). There was no significant association between asthma and SUI in the unadjusted (OR 1.15, 95% CI 0.96−1.38, p = 0.14) or adjusted model (OR 1.18, 95% CI 0.86−1.60, p = 0.30). Conclusion: Although a strong association between COPD and SUI was observed, an analogous one was not found between asthma and SUI. Chronic cough may be more difficult to control with treatment or more common in those with COPD than asthma, explaining this difference. Future research should continue to explore drivers for SUI in large populations to dispel or affirm historically assumed SUI risk factors.
AB - Introduction: There is a logical association between chronic obstructive pulmonary disease (COPD) or asthma with stress urinary incontinence (SUI), given the propensity for coughing which increases intra-abdominal pressure. However, there are few studies examining the association between COPD or asthma and specifically SUI. We aimed to utilize the National Health and Nutrition Examination Survey (NHANES) data from 2015 to 2020 to measure the association between respiratory diseases like COPD and asthma with SUI. Methods: Data was collected from NHANES, a database representative of the United States population. Participants were included if they were female, older than 20 years, and completed the incontinence survey question. Self-reported history of asthma and COPD diagnosis from a physician, as well as history of incontinence associated with activities such as coughing, lifting, or exercise, were collected. Characteristics of participants were compared using χ2 and Student t-tests. Multivariable logistic regression was performed using a multimodel approach to adjust for sociodemographic and health-related covariates. Results: A total of 9059 women were included in this study. 42.13% reported an episode of SUI in the past year, 6.29% had a COPD diagnosis, and 11.86% had an asthma diagnosis. In the unadjusted analysis, participants with COPD were more likely to report SUI (odds ratio [OR] 3.42, 95% confidence interval [CI] 2.13−5.49, p < 0.001); this association persisted on multivariable analysis (OR 2.87, 95% CI 1.46−5.60, p = 0.003). There was no significant association between asthma and SUI in the unadjusted (OR 1.15, 95% CI 0.96−1.38, p = 0.14) or adjusted model (OR 1.18, 95% CI 0.86−1.60, p = 0.30). Conclusion: Although a strong association between COPD and SUI was observed, an analogous one was not found between asthma and SUI. Chronic cough may be more difficult to control with treatment or more common in those with COPD than asthma, explaining this difference. Future research should continue to explore drivers for SUI in large populations to dispel or affirm historically assumed SUI risk factors.
KW - COPD
KW - NHANES
KW - asthma
KW - stress urinary incontinence
UR - http://www.scopus.com/inward/record.url?scp=85160094399&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85160094399&partnerID=8YFLogxK
U2 - 10.1002/nau.25217
DO - 10.1002/nau.25217
M3 - Article
C2 - 37226650
AN - SCOPUS:85160094399
SN - 0733-2467
VL - 42
SP - 1280
EP - 1289
JO - Neurourology and Urodynamics
JF - Neurourology and Urodynamics
IS - 6
ER -