Anticoagulation and Neuraxial/Peripheral Anesthesia

Mudit Kaushal, Ryan E. Rubin, Alan D. Kaye, Karina Gritsenko

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Novel anticoagulants (NAGs) have emerged as the preferred alternatives to vitamin K antagonists. In patients being considered for regional anesthesia, these drugs present a layer of complexity in the preprocedure evaluation. There are no established tests to monitor anticoagulant activity and our experience is short with these drugs. These authors believe it is important to review the relevant hematology, orthopedics, and anesthesiology literature to provide a valuable reference for the clinician who is met with these challenges. In addition to discussing NAGs, we also review the existing American Society of Regional Anesthesia guidelines for heparin, low-molecular-weight heparin, and antiplatelet agents.

Original languageEnglish (US)
Pages (from-to)e21-e39
JournalAnesthesiology Clinics
Issue number2
StatePublished - Jun 2017


  • Anticoagulation
  • Antiplatelet
  • Coumadin
  • Direct thrombin inhibitors
  • Factor Xa inhibitors
  • Neuraxial
  • Regional

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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