An unexpected bis-Ligation of S-nitrosothiols

Jiming Zhang, Hua Wang, Ming Xian

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


A bis-ligation reaction of S-nitrosothiols using triaryl substituted phosphine-thioester substrates has been developed. This reaction converts unstable primary S-nitrosothiols to stable disulfideiminophosphorane products in high yields under mild conditions. It can potentially be applied for the detection of S-nitrosation in protein systems.

Original languageEnglish (US)
Pages (from-to)3854-3855
Number of pages2
JournalJournal of the American Chemical Society
Issue number11
StatePublished - Mar 25 2009
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


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