An uncommon cause of lactic acidosis: MELAS

Ahmed Hussein, Rahil Kasmani, Farzan Irani, Geetali Mohan, Azza Ashmawy

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a rare clinical entity in adults transmitted by mitochondrial inheritance. Absence of family history and spatial distribution of clinical features can pose a diagnostic dilemma. We report a 36-year-old male who presented with recurrent strokes, seizures and lactic acidosis. A muscle biopsy revealed red ragged fibers pointing to the diagnosis of MELAS.

Original languageEnglish (US)
Pages (from-to)e114-e115
JournalEuropean Journal of Internal Medicine
Issue number5
StatePublished - Sep 2009
Externally publishedYes


  • Encephalopathy
  • Lactic acidosis
  • Stroke

ASJC Scopus subject areas

  • Internal Medicine


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