An uncommon cause of lactic acidosis: MELAS

Ahmed Hussein; Rahil Kasmani; Farzan Irani; Geetali Mohan; Azza Ashmawy

doi:10.1016/j.ejim.2008.09.018

An uncommon cause of lactic acidosis: MELAS

Ahmed Hussein, Rahil Kasmani, Farzan Irani, Geetali Mohan, Azza Ashmawy

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Abstract

Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a rare clinical entity in adults transmitted by mitochondrial inheritance. Absence of family history and spatial distribution of clinical features can pose a diagnostic dilemma. We report a 36-year-old male who presented with recurrent strokes, seizures and lactic acidosis. A muscle biopsy revealed red ragged fibers pointing to the diagnosis of MELAS.

Original language	English (US)
Pages (from-to)	e114-e115
Journal	European Journal of Internal Medicine
Volume	20
Issue number	5
DOIs	https://doi.org/10.1016/j.ejim.2008.09.018
State	Published - Sep 2009
Externally published	Yes

Keywords

Encephalopathy
Lactic acidosis
Stroke

ASJC Scopus subject areas

Internal Medicine

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10.1016/j.ejim.2008.09.018

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title = "An uncommon cause of lactic acidosis: MELAS",

abstract = "Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a rare clinical entity in adults transmitted by mitochondrial inheritance. Absence of family history and spatial distribution of clinical features can pose a diagnostic dilemma. We report a 36-year-old male who presented with recurrent strokes, seizures and lactic acidosis. A muscle biopsy revealed red ragged fibers pointing to the diagnosis of MELAS.",

keywords = "Encephalopathy, Lactic acidosis, Stroke",

author = "Ahmed Hussein and Rahil Kasmani and Farzan Irani and Geetali Mohan and Azza Ashmawy",

year = "2009",

month = sep,

doi = "10.1016/j.ejim.2008.09.018",

language = "English (US)",

volume = "20",

pages = "e114--e115",

journal = "European Journal of Internal Medicine",

issn = "0953-6205",

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TY - JOUR

T1 - An uncommon cause of lactic acidosis

T2 - MELAS

AU - Hussein, Ahmed

AU - Kasmani, Rahil

AU - Irani, Farzan

AU - Mohan, Geetali

AU - Ashmawy, Azza

PY - 2009/9

Y1 - 2009/9

N2 - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a rare clinical entity in adults transmitted by mitochondrial inheritance. Absence of family history and spatial distribution of clinical features can pose a diagnostic dilemma. We report a 36-year-old male who presented with recurrent strokes, seizures and lactic acidosis. A muscle biopsy revealed red ragged fibers pointing to the diagnosis of MELAS.

AB - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a rare clinical entity in adults transmitted by mitochondrial inheritance. Absence of family history and spatial distribution of clinical features can pose a diagnostic dilemma. We report a 36-year-old male who presented with recurrent strokes, seizures and lactic acidosis. A muscle biopsy revealed red ragged fibers pointing to the diagnosis of MELAS.

KW - Encephalopathy

KW - Lactic acidosis

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=68949176819&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=68949176819&partnerID=8YFLogxK

U2 - 10.1016/j.ejim.2008.09.018

DO - 10.1016/j.ejim.2008.09.018

M3 - Letter

C2 - 19712829

AN - SCOPUS:68949176819

SN - 0953-6205

VL - 20

SP - e114-e115

JO - European Journal of Internal Medicine

JF - European Journal of Internal Medicine

IS - 5

ER -

An uncommon cause of lactic acidosis: MELAS

Abstract

Keywords

ASJC Scopus subject areas

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