An Overview of Nanomaterials in Dermatology

Nanomaterials are materials that measure on the nanoscale (1-100. nm) or materials that contain nanoscale structures internally or on their surfaces. They include nanoparticles, nanoliposomes, nanoemulsions, nanoscaffolds, nanopigments, and quantum dots, to name a few, which can be engineered with a variety of chemical compositions and surface characteristics. Nanodermatology, an emerging field, employs nanomaterials for diagnostic, therapeutic, and cosmetic applications in dermatology. Nanomaterials demonstrate potential for medical and commercial benefit due to their large surface area, unique surface reactivity, and ability to overcome stability-solubility barriers of active agents via nanoencapsulation and sustained-release activity. Furthermore, their capacity for molecular targeting and selective accumulation within tissues can enhance the specificity of current interventions. To capitalize on the benefits of nanomaterials, which have been demonstrated in numerous recent studies, clinical trials are needed to determine their clinical translatability. The development of standardized methodology for determining nanomaterial safety in humans is also warranted.