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Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress

  • Rajarshi Ghosh
  • , Likun Wang
  • , Eric S. Wang
  • , B. Gayani K. Perera
  • , Aeid Igbaria
  • , Shuhei Morita
  • , Kris Prado
  • , Maike Thamsen
  • , Deborah Caswell
  • , Hector Macias
  • , Kurt F. Weiberth
  • , Micah J. Gliedt
  • , Marcel V. Alavi
  • , Sanjay B. Hari
  • , Arinjay K. Mitra
  • , Barun Bhhatarai
  • , Stephan C. Schürer
  • , Erik L. Snapp
  • , Douglas B. Gould
  • , Michael S. German
  • Bradley J. Backes, Dustin J. Maly, Scott A. Oakes, Feroz R. Papa

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Biochemistry, Genetics and Molecular Biology