Aging: One thing leads to another

Marion Schmidt, Brian K. Kennedy

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations


Mitochondria deteriorate during the aging process, but the underlying mechanisms for the decline of this critical organelle are unknown. A new study indicates that in yeast an age-dependent reduction in vacuolar acidification leads to mitochondrial dysfunction through a surprising mechanism: loss of vacuolar neutral amino acid transport.

Original languageEnglish (US)
Pages (from-to)R1048-R1051
JournalCurrent Biology
Issue number24
StatePublished - Dec 18 2012
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)


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