Affinity measured by microcluster

David R. Fooksman; Michael L. Dustin

doi:10.1084/jem.20100780

Affinity measured by microcluster

David R. Fooksman, Michael L. Dustin

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

Original language	English (US)
Pages (from-to)	907-909
Number of pages	3
Journal	Journal of Experimental Medicine
Volume	207
Issue number	5
DOIs	https://doi.org/10.1084/jem.20100780
State	Published - May 10 2010
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1084/jem.20100780

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title = "Affinity measured by microcluster",

abstract = "Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation {"}translate{"} BCR affinity for antigen into B cell responsiveness.",

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volume = "207",

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AU - Fooksman, David R.

AU - Dustin, Michael L.

PY - 2010/5/10

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N2 - Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

AB - Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

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U2 - 10.1084/jem.20100780

DO - 10.1084/jem.20100780

M3 - Comment/debate

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VL - 207

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JO - Journal of Experimental Medicine

JF - Journal of Experimental Medicine

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Affinity measured by microcluster

Abstract

ASJC Scopus subject areas

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