Abstract
Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article, we attempt to provide a brief overview on the recent progress in the field, current understanding of the underlying mechanisms of the approach, and the potential of stem cell-based therapies beyond cell implantation. We conclude the review by sharing our viewpoints on the challenges, opportunities, and future directions of this approach. The translational potential of this article: This paper reviews recent progress on stem cell-based therapeutic approaches for tendon repair, which highlights its translational potential and challenges.
Original language | English (US) |
---|---|
Pages (from-to) | 69-75 |
Number of pages | 7 |
Journal | Journal of Orthopaedic Translation |
Volume | 9 |
DOIs | |
State | Published - Apr 1 2017 |
Keywords
- stem cells
- tendinopathy
- tendon repair
ASJC Scopus subject areas
- Orthopedics and Sports Medicine