Abstract
This report describes a 4-month-old infant with multisystem organ failure who developed severe hypernatremia (sodium 168 mEq/l) due to rapid free water removal associated with acute peritoneal dialysis instituted for fluid overload. The current report describes the pathophysiology of the hypernatremia, and its correction by low-sodium hypertonic peritoneal dialysis without compromising ultrafiltration or supplementing with free water. Although peritoneal dialysis can cause hypernatremia, a modified solute concentration in the dialysate can treat the hypernatremia successfully. This report describes a child with multi-system organ failure due to cardiogenic shock who developed severe hypernatremia secondary to aggressive fluid removal from acute peritoneal dialysis to treat anasarca. A mechanism for the development of hypernatremia is proposed. In addition, a method to adjust the solute concentration of the dialysate is proposed to effect successful therapy without compromising fluid removal or providing additional free water.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 697-700 |
| Number of pages | 4 |
| Journal | Pediatric Nephrology |
| Volume | 16 |
| Issue number | 9 |
| DOIs | |
| State | Published - 2001 |
| Externally published | Yes |
Keywords
- Critically ill
- Edema
- Hypernatremia
- Infant
- Peritoneal dialysis
- Sodium
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Nephrology