Acute hyperkalemia and hyponatremia following intraoperative mannitol administration

Jyotsna Rimal, Sergey V. Pisklakov, Heidi Boules, Anuradha Patel

Research output: Contribution to journalArticlepeer-review


Intravenous mannitol may lead to electrolyte disturbances involving sodium and potassium and resulting in cardiac dysfunction. This report demonstrates that when mannitol is given during intracranial surgery it can cause large increase potassium ion concentration and decrease in sodium ion concentration in the absence of any other possible causes. Intraoperative checks of serum electrolyte levels, arterial blood gas analysis and electrocardiogram monitoring could be recommended to be done routinely when using mannitol.

Original languageEnglish (US)
JournalJournal of Anesthesia and Clinical Research
Issue number3
StatePublished - Mar 2013
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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