Abstract
Background: Abruptio placentae is a serious problem with a high rate of maternal and fetal mortality and documented sexual dimorphism in reoccurrence. Macaca fascicularis is a well-described reproductive model; however, there are no data available regarding sexual dimorphism in abruptio placentae in these species. Methods: A retrospective study of pathology and medical records in a large colony of M. fascicularis was performed. Placental specimens were analyzed. Results: The incidence of placenta abruptio in the colony was 15.7/1000 births. In the abruptio placentae group, male fetuses had lower placental disk length and increased femur length compared with female fetuses. The feto-pacental ratio and fetal weight were lower in the male fetuses in the abruption group compared with those in the stillbirth group without abruption placentae. Conclusion: This is the first documentation of male bias in placental and fetal development in abruptio placentae in non-human primates.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 204-210 |
| Number of pages | 7 |
| Journal | Journal of Medical Primatology |
| Volume | 42 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2013 |
| Externally published | Yes |
Keywords
- Complications
- Non-human primate
- Placenta
- Pregnancy
- Sexual dimorphism
ASJC Scopus subject areas
- Animal Science and Zoology
- General Veterinary
