Ablation for atrial fibrillation: Termination of atrial fibrillation is not the end point

Pasquale Santangeli; Luigi Di Biase; Amin Al-Ahmad; Rodney Horton; J. David Burkhardt; Javier E. Sanchez; Rong Bai; Agnes Pump; Sanghamitra Mohanty; Andrea Natale

doi:10.1016/j.ccep.2012.06.005

Ablation for atrial fibrillation: Termination of atrial fibrillation is not the end point

Pasquale Santangeli, Luigi Di Biase, Amin Al-Ahmad, Rodney Horton, J. David Burkhardt, Javier E. Sanchez, Rong Bai, Agnes Pump, Sanghamitra Mohanty, Andrea Natale

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Permanent pulmonary vein isolation constitutes the main procedural goal of current approaches to atrial fibrillation (AF) catheter ablation, with established effectiveness as a stand-alone procedure in most patients with paroxysmal AF. In patients with AF of longer duration, however, the definition of the optimal procedural end point is still controversial. Based on analysis of data from 16 studies that have assessed the value of AF termination in predicting long-term procedural success, it is concluded that AF termination clearly represents an unreliable procedural end point during ablation of nonparoxysmal AF.

Original language	English (US)
Pages (from-to)	343-352
Number of pages	10
Journal	Cardiac Electrophysiology Clinics
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/j.ccep.2012.06.005
State	Published - Sep 2012
Externally published	Yes

Keywords

Catheter ablation
Nonparoxysmal atrial fibrillation
Procedural end point
Pulmonary vein isolation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1016/j.ccep.2012.06.005

Cite this

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title = "Ablation for atrial fibrillation: Termination of atrial fibrillation is not the end point",

abstract = "Permanent pulmonary vein isolation constitutes the main procedural goal of current approaches to atrial fibrillation (AF) catheter ablation, with established effectiveness as a stand-alone procedure in most patients with paroxysmal AF. In patients with AF of longer duration, however, the definition of the optimal procedural end point is still controversial. Based on analysis of data from 16 studies that have assessed the value of AF termination in predicting long-term procedural success, it is concluded that AF termination clearly represents an unreliable procedural end point during ablation of nonparoxysmal AF.",

keywords = "Catheter ablation, Nonparoxysmal atrial fibrillation, Procedural end point, Pulmonary vein isolation",

author = "Pasquale Santangeli and {Di Biase}, Luigi and Amin Al-Ahmad and Rodney Horton and Burkhardt, {J. David} and Sanchez, {Javier E.} and Rong Bai and Agnes Pump and Sanghamitra Mohanty and Andrea Natale",

year = "2012",

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doi = "10.1016/j.ccep.2012.06.005",

language = "English (US)",

volume = "4",

pages = "343--352",

journal = "Cardiac Electrophysiology Clinics",

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TY - JOUR

T1 - Ablation for atrial fibrillation

T2 - Termination of atrial fibrillation is not the end point

AU - Santangeli, Pasquale

AU - Di Biase, Luigi

AU - Al-Ahmad, Amin

AU - Horton, Rodney

AU - Burkhardt, J. David

AU - Sanchez, Javier E.

AU - Bai, Rong

AU - Pump, Agnes

AU - Mohanty, Sanghamitra

AU - Natale, Andrea

PY - 2012/9

Y1 - 2012/9

N2 - Permanent pulmonary vein isolation constitutes the main procedural goal of current approaches to atrial fibrillation (AF) catheter ablation, with established effectiveness as a stand-alone procedure in most patients with paroxysmal AF. In patients with AF of longer duration, however, the definition of the optimal procedural end point is still controversial. Based on analysis of data from 16 studies that have assessed the value of AF termination in predicting long-term procedural success, it is concluded that AF termination clearly represents an unreliable procedural end point during ablation of nonparoxysmal AF.

AB - Permanent pulmonary vein isolation constitutes the main procedural goal of current approaches to atrial fibrillation (AF) catheter ablation, with established effectiveness as a stand-alone procedure in most patients with paroxysmal AF. In patients with AF of longer duration, however, the definition of the optimal procedural end point is still controversial. Based on analysis of data from 16 studies that have assessed the value of AF termination in predicting long-term procedural success, it is concluded that AF termination clearly represents an unreliable procedural end point during ablation of nonparoxysmal AF.

KW - Catheter ablation

KW - Nonparoxysmal atrial fibrillation

KW - Procedural end point

KW - Pulmonary vein isolation

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DO - 10.1016/j.ccep.2012.06.005

M3 - Review article

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SN - 1877-9182

VL - 4

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JF - Cardiac Electrophysiology Clinics

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ER -

Ablation for atrial fibrillation: Termination of atrial fibrillation is not the end point

Abstract

Keywords

ASJC Scopus subject areas

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