Ablation as First-Line Therapy for Atrial Fibrillation: Yes

Pasquale Santangeli; Luigi Di Biase; Amin Al-Ahmad; Rodney Horton; J. David Burkhardt; Javier E. Sanchez; G. Joseph Gallinghouse; Jason Zagrodzky; Rong Bai; Agnes Pump; Sanghamitra Mohanty; William R. Lewis; Andrea Natale

doi:10.1016/j.ccep.2012.05.011

Ablation as First-Line Therapy for Atrial Fibrillation: Yes

Pasquale Santangeli, Luigi Di Biase, Amin Al-Ahmad, Rodney Horton, J. David Burkhardt, Javier E. Sanchez, G. Joseph Gallinghouse, Jason Zagrodzky, Rong Bai, Agnes Pump, Sanghamitra Mohanty, William R. Lewis, Andrea Natale

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

This article addresses the use of catheter ablation (CA) as first-line therapy for atrial fibrillation (AF). CA increases long-term freedom from AF, reduces hospitalizations, and improves quality of life compared with antiarrhythmic drug (AAD) therapy in patients with symptomatic AF who have already failed one AAD. The role of CA as first-line therapy for AF, however, is still controversial. Evidence from randomized controlled trials shows that CA is definitely superior to AADs as first-line therapy for relatively young patients with paroxysmal AF, with comparable complication rates and results consistently reproducible across different institutions, operators, and types of ablation approaches.

Original language	English (US)
Pages (from-to)	287-297
Number of pages	11
Journal	Cardiac Electrophysiology Clinics
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/j.ccep.2012.05.011
State	Published - Sep 2012
Externally published	Yes

Keywords

Atrial fibrillation
Catheter ablation
First-line therapy

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1016/j.ccep.2012.05.011

Cite this

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title = "Ablation as First-Line Therapy for Atrial Fibrillation: Yes",

abstract = "This article addresses the use of catheter ablation (CA) as first-line therapy for atrial fibrillation (AF). CA increases long-term freedom from AF, reduces hospitalizations, and improves quality of life compared with antiarrhythmic drug (AAD) therapy in patients with symptomatic AF who have already failed one AAD. The role of CA as first-line therapy for AF, however, is still controversial. Evidence from randomized controlled trials shows that CA is definitely superior to AADs as first-line therapy for relatively young patients with paroxysmal AF, with comparable complication rates and results consistently reproducible across different institutions, operators, and types of ablation approaches.",

keywords = "Atrial fibrillation, Catheter ablation, First-line therapy",

author = "Pasquale Santangeli and {Di Biase}, Luigi and Amin Al-Ahmad and Rodney Horton and Burkhardt, {J. David} and Sanchez, {Javier E.} and Gallinghouse, {G. Joseph} and Jason Zagrodzky and Rong Bai and Agnes Pump and Sanghamitra Mohanty and Lewis, {William R.} and Andrea Natale",

year = "2012",

month = sep,

doi = "10.1016/j.ccep.2012.05.011",

language = "English (US)",

volume = "4",

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journal = "Cardiac Electrophysiology Clinics",

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T2 - Yes

AU - Santangeli, Pasquale

AU - Di Biase, Luigi

AU - Al-Ahmad, Amin

AU - Horton, Rodney

AU - Burkhardt, J. David

AU - Sanchez, Javier E.

AU - Gallinghouse, G. Joseph

AU - Zagrodzky, Jason

AU - Bai, Rong

AU - Pump, Agnes

AU - Mohanty, Sanghamitra

AU - Lewis, William R.

AU - Natale, Andrea

PY - 2012/9

Y1 - 2012/9

N2 - This article addresses the use of catheter ablation (CA) as first-line therapy for atrial fibrillation (AF). CA increases long-term freedom from AF, reduces hospitalizations, and improves quality of life compared with antiarrhythmic drug (AAD) therapy in patients with symptomatic AF who have already failed one AAD. The role of CA as first-line therapy for AF, however, is still controversial. Evidence from randomized controlled trials shows that CA is definitely superior to AADs as first-line therapy for relatively young patients with paroxysmal AF, with comparable complication rates and results consistently reproducible across different institutions, operators, and types of ablation approaches.

AB - This article addresses the use of catheter ablation (CA) as first-line therapy for atrial fibrillation (AF). CA increases long-term freedom from AF, reduces hospitalizations, and improves quality of life compared with antiarrhythmic drug (AAD) therapy in patients with symptomatic AF who have already failed one AAD. The role of CA as first-line therapy for AF, however, is still controversial. Evidence from randomized controlled trials shows that CA is definitely superior to AADs as first-line therapy for relatively young patients with paroxysmal AF, with comparable complication rates and results consistently reproducible across different institutions, operators, and types of ablation approaches.

KW - Atrial fibrillation

KW - Catheter ablation

KW - First-line therapy

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JO - Cardiac Electrophysiology Clinics

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Ablation as First-Line Therapy for Atrial Fibrillation: Yes

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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