A New Quassinoid from Brucea javanica

Jun Li, Dayong Zheng, Ning Wei, Yunfeng Sun, Li Liu, Yuan Yuan, Qinghua Jiang

Research output: Contribution to journalArticlepeer-review


A new quassinoid, dehydrobruceantinol B (1), was isolated from the seeds of Brucea javanica, together with two known compounds, bruceantinol (2) and bruceine A (3). The structure of the new compound 1 was elucidated by advanced spectrometric methods, including HR-MS, UV, IR, 1D and 2D NMR experiments. The inhibitory effects of 1–3 on nitric oxide production in lipopolysaccharide-activated macrophages were also investigated in this study.

Original languageEnglish (US)
Pages (from-to)650-652
Number of pages3
JournalChemistry of Natural Compounds
Issue number4
StatePublished - Jul 2022
Externally publishedYes


  • Brucea javanica
  • Simaroubaceae
  • nitric oxide production
  • quassinoid

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Plant Science


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