A new iron-binding protein isolated from intestinal mucosa

Simeon Pollack, Fred D. Lasky

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


A new iron-binding protein contained in guinea pig intestinal mucosa has been purified to homogeneity. The protein has a molecular weight of 78,000 in a nondissociating system and 43,000 in SDS-gel electrophoresis. It binds approximately 2 moles of iron per mole with a formation constant of 1019 at pH 7. It is distinguished from transferrin and lactoferrin by differences on DEAE-Sephadex chromatography and spectroscopy and by its failure to cross-react with antisera to these other iron-binding proteins.

Original languageEnglish (US)
Pages (from-to)670-679
Number of pages10
JournalThe Journal of Laboratory and Clinical Medicine
Issue number4
StatePublished - Apr 1976

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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