TY - JOUR
T1 - A longitudinal examination of parent-reported emotional-behavioral functioning of children with mild to moderate chronic kidney disease
AU - Johnson, Rebecca J.
AU - Gerson, Arlene C.
AU - Harshman, Lyndsay A.
AU - Matheson, Matthew B.
AU - Shinnar, Shlomo
AU - Lande, Marc B.
AU - Kogon, Amy
AU - Gipson, Debbie S.
AU - Warady, Bradley A.
AU - Furth, Susan L.
AU - Hooper, Stephen R.
N1 - Publisher Copyright:
© 2020, IPNA.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Background: Children with mild to moderate chronic kidney disease (CKD) are at increased risk for deficits in neurocognition. Less is known about how CKD affects emotional-behavioral functioning in this population. Methods: Parent ratings of emotional-behavioral functioning at baseline and over time were examined for 845 children with mild to moderate CKD using the Behavior Assessment System for Children, Second Edition Parent Rating Scales (BASC-2 PRS). Associations with demographic and disease-related predictors were also examined. Results: Children with mild to moderate CKD had parent-reported emotional-behavioral functioning largely within normal limits, at baseline and over time. The proportion with T-scores at least 1 SD above the mean was 24% for Internalizing Problems and 28% for Attention Problems. A greater proportion of participants scored lower than expected (worse) on scales measuring adaptive skills (25%). Persistent hypertension predicted attention problems (β = 1.59, 95% CI = 0.24 to 2.94, p < 0.02) and suggested worse behavioral symptoms (β = 1.36, 95% CI = − 0.01 to 2.73, p = 0.05). Participants with proteinuria at baseline, but not at follow-up, had fewer attention problems than participants whose proteinuria had not resolved (β = − 3.48, CI = − 6.79 to − 0.17, p < 0.04). Glomerular diagnosis was related to fewer (β = − 2.68, 95% CI = − 4.93 to − 0.42, p < 0.02) internalizing problems. Conclusions: Although children with CKD generally have average emotional-behavioral parent ratings, a notable percentage of the population may be at risk for problems with attention and adaptive behavior. Providers working with this population should facilitate psychosocial referrals when indicated.
AB - Background: Children with mild to moderate chronic kidney disease (CKD) are at increased risk for deficits in neurocognition. Less is known about how CKD affects emotional-behavioral functioning in this population. Methods: Parent ratings of emotional-behavioral functioning at baseline and over time were examined for 845 children with mild to moderate CKD using the Behavior Assessment System for Children, Second Edition Parent Rating Scales (BASC-2 PRS). Associations with demographic and disease-related predictors were also examined. Results: Children with mild to moderate CKD had parent-reported emotional-behavioral functioning largely within normal limits, at baseline and over time. The proportion with T-scores at least 1 SD above the mean was 24% for Internalizing Problems and 28% for Attention Problems. A greater proportion of participants scored lower than expected (worse) on scales measuring adaptive skills (25%). Persistent hypertension predicted attention problems (β = 1.59, 95% CI = 0.24 to 2.94, p < 0.02) and suggested worse behavioral symptoms (β = 1.36, 95% CI = − 0.01 to 2.73, p = 0.05). Participants with proteinuria at baseline, but not at follow-up, had fewer attention problems than participants whose proteinuria had not resolved (β = − 3.48, CI = − 6.79 to − 0.17, p < 0.04). Glomerular diagnosis was related to fewer (β = − 2.68, 95% CI = − 4.93 to − 0.42, p < 0.02) internalizing problems. Conclusions: Although children with CKD generally have average emotional-behavioral parent ratings, a notable percentage of the population may be at risk for problems with attention and adaptive behavior. Providers working with this population should facilitate psychosocial referrals when indicated.
KW - Adaptive behavior
KW - BASC-2
KW - CKD
KW - CKiD
KW - Emotional-behavioral
KW - Pediatric chronic kidney disease
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U2 - 10.1007/s00467-020-04511-9
DO - 10.1007/s00467-020-04511-9
M3 - Article
C2 - 32157444
AN - SCOPUS:85081238657
SN - 0931-041X
VL - 35
SP - 1287
EP - 1295
JO - Pediatric Nephrology
JF - Pediatric Nephrology
IS - 7
ER -