A case of renal cell carcinoma after successful treatment of Wilms tumor

Barrie S. Rich, Maureen P. McEvoy, Michael P. La Quaglia

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


This case report documents the eighth reported case of renal cell carcinoma (RCC) occurring after treatment of Wilms tumor. Although secondary malignancies after treatment of Wilms tumors are not infrequent, RCC as the second malignancy is rare. We discuss a 17-year-old girl whose RCC was diagnosed 12.5 years after diagnosis of a Wilms tumor. In addition, we review the literature on the subject. Renal cell carcinoma has been proposed as a consequent of chemoradiation; however, a genetic susceptibility must be considered. Because it is routine to assess the functional status of the remaining solitary kidney by annual ultrasonography, we recommend assessing for the presence of secondary renal malignancies and perhaps continuing routine ultrasounds long-term.

Original languageEnglish (US)
Pages (from-to)1883-1886
Number of pages4
JournalJournal of Pediatric Surgery
Issue number9
StatePublished - Sep 1 2010
Externally publishedYes


  • Renal cell carcinoma
  • Secondary malignancy
  • Wilms tumor

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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