Mechanism of Microtubule Dynamics Regulation by Kinesins

  • Sosa, Hernando H.J (PI)
  • Sosa, Hernando Jose (CoPI)

Project: Research project

Project Details

Description

The proposed work will investigate the molecular structure and mechanism of action of a group of kinesin proteins that modulate the ability of the microtubular cytoskeleton to elongate and shrink. Due to the role that these kinesins have in cell division and tumor growth they are also attractive targets for the development of anti-cancer drugs. Thus, the proposed studies may help the rational design of a new generation of drugs to treat cancer.
StatusFinished
Effective start/end date3/1/151/31/23

Funding

  • National Institute of General Medical Sciences: $31,504.00
  • National Institute of General Medical Sciences: $66,925.00
  • National Institute of General Medical Sciences: $442,550.00
  • National Institute of General Medical Sciences: $398,297.00
  • National Institute of General Medical Sciences: $202,070.00
  • National Institute of General Medical Sciences: $360,495.00
  • National Institute of General Medical Sciences: $404,140.00
  • National Institute of General Medical Sciences: $398,296.00
  • National Institute of General Medical Sciences: $202,070.00
  • National Institute of General Medical Sciences: $442,550.00
  • National Institute of General Medical Sciences: $404,140.00

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