Keyphrases
Catalytic Mechanism
100%
Regulatory Mechanism
100%
Tryptophan 2,3-dioxygenase (TDO2)
100%
Dioxygenase
21%
Neurodegenerative Diseases
14%
Structural Features
14%
Liver
14%
Cell Degradation
14%
Tumor Immunity
7%
Regulation Mechanism
7%
3D Structure
7%
Alzheimer's Disease
7%
Degradation Pathway
7%
Ubiquitination
7%
Kynurenine Pathway
7%
Catalytic Activity
7%
Human Tumors
7%
Therapeutic Target
7%
Tumor Growth
7%
Homeostasis
7%
Heme Proteins
7%
Activation Mechanism
7%
Aggressive Tumor
7%
Specific Intent
7%
Single Crystal
7%
Huntington's Disease
7%
Unusual Activity
7%
Exosite
7%
Comprehensive Approach
7%
Selective Inhibitor
7%
Dioxygen Activation
7%
Trapping Reactions
7%
Molecular Properties
7%
Essential Enzymes
7%
Heme
7%
Reaction Intermediates
7%
Release Mechanism
7%
N-formylkynurenine
7%
Rate-limiting Step
7%
Unique Perspectives
7%
Proteasomal Degradation
7%
Product Release
7%
Biochemistry, Genetics and Molecular Biology
Tryptophan
100%
Dioxygenase
100%
Enzyme
29%
Tumor Progression
5%
Hemeprotein
5%
Ubiquitination
5%
Homeostasis
5%
Exosite
5%
Kynurenine Pathway
5%
Enzymatic Activity
5%
Kynurenine
5%
Hemoprotein
5%