Variation of gap junction sensitivity to H ions with time of day

A. P. Moreno, F. Ramon, D. C. Spray

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Conductance of gap junctions between segments of the lateral axons of the crayfish nerve cord is reduced by cytoplasmic acidification. Simultaneous measurements of axoplasmic pH and junctional conductance at 09.00 and 12.00 h revealed a shift of about 0.25 pH units in the apparent pK of the crayfish electronic synapse. These findings indicate that gating mechanisms of gap junctions are not fixed properties, but may rather be modulated by other, possibly humoral, factors.

Original languageEnglish (US)
Pages (from-to)181-184
Number of pages4
JournalBrain research
Issue number1
StatePublished - Jan 1 1987


  • Diurnal rhythm
  • Electrotonic synapse
  • Gap junction
  • pH

ASJC Scopus subject areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology


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