Urine Proteomics Link Complement Activation with Interstitial Fibrosis/Tubular Atrophy in Lupus Nephritis Patients

Keyphrases

• Lupus Nephritis 100%
• Complement Activation 100%
• Tubulointerstitial Fibrosis 100%
• Urine Proteome 100%
• Link Complement 100%
• Tubular Atrophy 91%
• Interstitial Fibrosis 91%
• CD59 58%
• Platelet-derived Growth factor-BB (PDGF-BB) 25%
• Membrane Attack Complex 25%
• Platelet-derived Growth Factor Receptor β 25%
• Complement Components 16%
• Kidney Biopsy 16%
• Interstitium 16%
• Self-identification 16%
• Mass Spectrometry 8%
• African American 8%
• Cell Membrane 8%
• Pediatric 8%
• Complex Formation 8%
• Serum Creatinine 8%
• Human Tissue 8%
• Clinically Indicated 8%
• Kidney Fibrosis 8%
• Urine Samples 8%
• Hispanic Americans 8%
• Proteomic Analysis 8%
• Transforming Growth Factor Receptor 8%
• Intrarenal 8%
• Patients Included 8%
• Biopsy-proven 8%
• Complex Activation 8%
• Cell Lysis 8%
• Complement Proteins 8%
• Complement C9 8%
• Orbitrap Fusion Lumos 8%
• Complement Inhibition 8%
• Protein-enriched 8%
• Proteome Discoverer 8%

Medicine and Dentistry

• Idiopathic Pulmonary Fibrosis 100%
• Lupus Nephritis 100%
• Complement Activation 100%
• Proteomics 100%
• Urinary System 50%
• Platelet Derived Growth Factor 25%
• Complement Membrane Attack Complex 25%
• Platelet Derived Growth Factor Beta Receptor 25%
• Fibrosis 16%
• Renal Biopsy 16%
• Interstitium 16%
• Complement 16%
• Cell Membrane 8%
• Mediator 8%
• Pediatrics 8%
• Creatinine 8%
• Complex Formation 8%
• Urine Sampling 8%
• Cytolysis 8%
• Biopsy Technique 8%
• Human Tissue 8%
• Kidney Fibrosis 8%
• Complement Component C9 8%
• Complement Component C5b 8%
• Complement Inhibition 8%
• Transforming Growth Factor Beta Receptor 8%
• Orbitrap Mass Spectrometry 8%
• Proteome 8%
• Pathogenesis 8%

Immunology and Microbiology

• Lupus Erythematosus 100%
• Nephritis 100%
• Complement Activation 100%
• Proteomics 100%
• CD59 58%
• Platelet Derived Growth Factor Beta Receptor 33%
• Complement Membrane Attack Complex 25%
• Interstitium 16%
• Complement 16%
• Platelet Derived Growth Factor 16%
• Cytolysis 8%
• Cell Membrane 8%
• Mediator 8%
• Creatinine Blood Level 8%
• Complex Formation 8%
• Animal Experiment 8%
• Human Tissue 8%
• Urine Sampling 8%
• Cancer Growth Factor 8%
• Complement Component C9 8%
• Complement Component C5b 8%
• Orbitrap Mass Spectrometry 8%
• Complement Inhibition 8%