@article{08b22972c77a47e6bc6b6519f1f80535,
title = "Understanding the Targeting Mechanisms of Multi-Specific Biologics in Immunotherapy with Multiscale Modeling",
abstract = "Immunology;",
keywords = "Immunology, Therapeutics",
author = "Zhaoqian Su and Bo Wang and Almo, {Steven C.} and Yinghao Wu",
note = "Funding Information: This work was supported by the National Institutes of Health under Grant Numbers R01GM120238 (to Y.W.), R01AI145024 , and R01CA198095 (to S.C.A.). We acknowledge the Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology (to S.C.A.), Janet and Martin Spatz, and the Helen and Irving Spatz Foundation. We also acknowledge the Einstein-Rockefeller-CUNY Center for AIDS Research (P30AI124414) and the Albert Einstein Cancer Center (P30CA013330). The work is also partially supported by a start-up grant from the Albert Einstein College of Medicine . Computational support was provided by the Albert Einstein College of Medicine High Performance Computing Center. Finally, Anton 2 computer time was provided by the Pittsburgh Supercomputing Center (PSC) through Grant R01GM116961 from the National Institutes of Health . The Anton 2 machine at the PSC was generously made available by D.E. Shaw Research. Publisher Copyright: {\textcopyright} 2020 The Author(s)",
year = "2020",
month = dec,
day = "18",
doi = "10.1016/j.isci.2020.101835",
language = "English (US)",
volume = "23",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier Inc.",
number = "12",
}