Transition-state analysis of S. pneumoniae 5′-methylthioadenosine nucleosidase

Medicine & Life Sciences

• 5'-methylthioadenosine 100%
• 5'-methylthioadenosine phosphorylase 100%
• Adenine 11%
• adenosylhomocysteine nucleosidase 30%
• Density Functional Theory 8%
• Escherichia coli 6%
• Hydroxyl Radical 15%
• Ions 7%
• Isotopes 61%
• Kinetics 30%
• Pemetrexed 6%
• Pneumonia 45%
• Sulfur 5%
• Water 3%

Chemical Compounds

• Adenine 11%
• Density Functional Theory 3%
• Dielectric Constant 5%
• Dihedral Angle 5%
• Dipole Interaction 7%
• Hydroxyl 5%
• Hyperconjugation 16%
• Ion 2%
• Isotope Effect 19%
• Kinetic Isotope Effect 61%
• Nucleophile 5%
• Orbital 5%
• Polarization 14%
• Solvent 2%
• Torsion 6%
• Transition State 46%

Engineering & Materials Science

• Atoms 4%
• Conformations 5%
• Dihedral angle 7%
• Discrete Fourier transforms 5%
• Escherichia coli 11%
• Ions 8%
• Isotopes 69%
• Nucleophiles 9%
• Permittivity 4%
• Polarization 12%
• Sulfur 4%
• Torsional stress 4%
• Water 2%