Transient hypothyroxinemia of prematurity

Edmund F. La Gamma; Steven J. Korzeniewski; Praveen Ballabh; Nigel Paneth

doi:10.1542/neo.17-7-e394

Transient hypothyroxinemia of prematurity

Edmund F. La Gamma
, Steven J. Korzeniewski
, Praveen Ballabh
, Nigel Paneth

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Thyroid hormones play an important role in central nervous system development, starting from the exclusive maternal contribution in the first trimester and transitioning to a fully independent servo-control system at term birth. Extremely preterm delivery before 28 weeks’ gestational age disrupts this normal transition and reveals the challenge of whether replacement hormone will benefit cognitive and motor development. Although the evidence regarding deficiency is compelling, the hormone replacement question remains unanswered for preterm neonates.

Original language	English (US)
Pages (from-to)	e394-e402
Journal	Pediatrics in Review
Volume	17
Issue number	7
DOIs	https://doi.org/10.1542/neo.17-7-e394
State	Published - 2016
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1542/neo.17-7-e394

Cite this

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abstract = "Thyroid hormones play an important role in central nervous system development, starting from the exclusive maternal contribution in the first trimester and transitioning to a fully independent servo-control system at term birth. Extremely preterm delivery before 28 weeks{\textquoteright} gestational age disrupts this normal transition and reveals the challenge of whether replacement hormone will benefit cognitive and motor development. Although the evidence regarding deficiency is compelling, the hormone replacement question remains unanswered for preterm neonates.",

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AU - Ballabh, Praveen

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AB - Thyroid hormones play an important role in central nervous system development, starting from the exclusive maternal contribution in the first trimester and transitioning to a fully independent servo-control system at term birth. Extremely preterm delivery before 28 weeks’ gestational age disrupts this normal transition and reveals the challenge of whether replacement hormone will benefit cognitive and motor development. Although the evidence regarding deficiency is compelling, the hormone replacement question remains unanswered for preterm neonates.

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Transient hypothyroxinemia of prematurity

Abstract

ASJC Scopus subject areas

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