Transcriptional profiling of whole blood: A rich source of immune biomarkers in cancer

Y. Saenger; E. de Moll; Y. Fu

doi:10.4161/21624011.2014.944056

Transcriptional profiling of whole blood: A rich source of immune biomarkers in cancer

Y. Saenger, E. de Moll, Y. Fu

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Immunotherapy is at the forefront of cancer treatment, and biomarkers are urgently needed to predict patient response to therapy. Recently, we discovered a 4-gene peripheral blood mRNA signature for prolonged survival in patients treated with tremelimumab. Peripheral blood mRNA is a readily accessible and under-utilized source of clinically relevant biomarkers.

Original language	English (US)
Article number	e944056
Journal	OncoImmunology
Volume	3
Issue number	7
DOIs	https://doi.org/10.4161/21624011.2014.944056
State	Published - 2014
Externally published	Yes

Keywords

Biomarker
Immunotherapy
Peripheral blood
Tremelimumab
mRNA

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4161/21624011.2014.944056

Cite this

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title = "Transcriptional profiling of whole blood: A rich source of immune biomarkers in cancer",

abstract = "Immunotherapy is at the forefront of cancer treatment, and biomarkers are urgently needed to predict patient response to therapy. Recently, we discovered a 4-gene peripheral blood mRNA signature for prolonged survival in patients treated with tremelimumab. Peripheral blood mRNA is a readily accessible and under-utilized source of clinically relevant biomarkers.",

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N2 - Immunotherapy is at the forefront of cancer treatment, and biomarkers are urgently needed to predict patient response to therapy. Recently, we discovered a 4-gene peripheral blood mRNA signature for prolonged survival in patients treated with tremelimumab. Peripheral blood mRNA is a readily accessible and under-utilized source of clinically relevant biomarkers.

AB - Immunotherapy is at the forefront of cancer treatment, and biomarkers are urgently needed to predict patient response to therapy. Recently, we discovered a 4-gene peripheral blood mRNA signature for prolonged survival in patients treated with tremelimumab. Peripheral blood mRNA is a readily accessible and under-utilized source of clinically relevant biomarkers.

KW - Biomarker

KW - Immunotherapy

KW - Peripheral blood

KW - Tremelimumab

KW - mRNA

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Transcriptional profiling of whole blood: A rich source of immune biomarkers in cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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