Transcatheter edge-to-edge repair of the tricuspid valve: The US experience

Ramy Sedhom, Michael Megaly, Marwan Saad, Ayman Elbadawi, Christian F. Witzke, Santiago Garcia, Azeem Latib, Sameer A. Gafoor

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Objectives: To examine the trends in utilization and outcomes of tricuspid valve (TV) transcatheter edge-to-edge repair (TEER). Background: Surgery for isolated tricuspid regurgitation is associated with high morbidity and mortality and is rarely performed. TV TEER is an attractive alternative. Methods: The Nationwide Readmissions Database was queried using the International Classification of Diseases, 10th Revision, procedure code for TV TEER for years 2016–2019. The main outcomes were trends in utilization and in-hospital all-cause mortality. Results: We identified 918 hospitalizations for TV TEER. There was an uptrend in its utilization from 13 cases in the first quarter of 2016 to 122 cases in the last quarter of 2019 (p trend < 0.001). Concomitant mitral valve (MV) TEER was performed in 42.1% of admissions. The overall in-hospital mortality was 2.1%. Surgical TV replacement was needed in 1.1% of admissions; none of them died during the index hospitalization. Unplanned rehospitalizations were common at 30 days (15.7%); 38.2% of those were due to heart failure. There was no difference in in-hospital mortality between isolated TV TEER and combined MV and TV TEER (1.7% vs. 2.6%, p = 0.359). However, admissions receiving combined procedure had lower length of stay and urgent readmission rate. Conclusion: The current study showed that there was an increase in the utilization of TV TEER over 2016–2019 in the United States. TV TEER was associated with low rates of in-hospital mortality; however, the rate of urgent readmission remains high, mainly due to heart failure.

Original languageEnglish (US)
Pages (from-to)1859-1866
Number of pages8
JournalCatheterization and Cardiovascular Interventions
Issue number6
StatePublished - May 1 2022


  • MitraClip
  • Nationwide Readmission Database
  • tricuspid regurgitation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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