Tranexamic acid for major spine surgery

Sergey V. Pisklakov

Research output: Chapter in Book/Report/Conference proceedingChapter


A 55-year old man presents for elective L3-L5 lumbar laminectomy with decompression. His medical history consists of hypertension, well controlled with amlodipine. In addition, he suffers from chronic back pain due to lumbar radiculopathy and spinal stenosis. His laboratory work, including electrolytes, complete blood count, and coagulation factors, is normal. The surgeon is asking you to give the patient tranexamic acid (TXA) to reduce intraoperative bleeding. You wonder whether the benefits of TXA outweigh its downsides.

Original languageEnglish (US)
Title of host publicationYou're Wrong, I'm Right: Dueling Authors Reexamine Classic Teachings in Anesthesia
PublisherSpringer International Publishing
Number of pages3
ISBN (Electronic)9783319431697
ISBN (Print)9783319431673
StatePublished - Jan 1 2016


  • Fibrin
  • Hemorrhage
  • Pro-hemostatic therapy
  • Spine surgery
  • Tranexamic acid (TXA)

ASJC Scopus subject areas

  • Medicine(all)


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